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한국연구재단웹진5월호_카이스트 신중훈교수 연구팀





 

글로벌 인재가 많을수록 국 가의 경쟁력도 높아지듯이, 국가발전을 위한 최고의 경쟁력은 곧 '인재'이다. 세계 최고의 글로 벌 인재를 육성하기 위해 교육과학기술부와 한국연구재단이 지난 2008년부터 추진하기 시작한 사업이 곧 '세계 수준의 연 구중심대학(WCU, World Class University) 육성사업'이다. 이번 호에서는 WCU 육성사업의 지원으로 세계적 연구성과 도출과 신진 우수과학자 양성을 위해 최선의 노력을 경주하고 있는 카이스트 신중훈 교수 연구팀의 연구 이야기를 들어보자~

  

'세계 수준의 연구중심대학 (WCU) 육성사업'은 미래 국가발전 핵심분야에 대한 연구를 수행하고, 학문후속세대를 양성하고 자 교과부와 연구재단이 공동으로 추진하고 있는 사업이다. 현재 국제적 수준이나 질적 수준이 미흡한 분야를 더욱 활성 화시켜 교수와 연구자 중심의 지원을 늘리고, 연구역량이 높은 해외학자를 확보하여, 국내대학의 교육과 연구 풍토 혁신을 기대하고 있 다.

그 결과 창의적 연구역량을 갖춘 세계 수준의 연구중심대학이 육성되고, 해외로 유출되던 인재를 국내에서 양성할 수 있으 며, 세계 대학과의 경쟁에서 결코 뒤지지 않는 명문대학이 만들어져, 국내 대학을 졸업해도 세계적인 연구자로 도약할 수 있 는 계기가 마련될 것으로 기대된다. 이러한 연구 목적 하에, 지난해부터 2012년까지 WCU 육성사업을 지원 받고 있는 카이스트 신중훈 교수팀은 해외석 학과의 공동연구를 통해 국제적 협력 관계를 구축하고, 우리나라 과학기술 발전을 위한 핵심기술 개발과 글로벌 인재 양성을 위해 매진하고 있다.

  

카이스트 신중훈 교수팀의 연구주제는 '나노바이오 융합 연구'이다. 자연과학의 근본적 원리에 기반을 두고, 기초적인 바 이오 물질의 구조 분석에서부터, 나노소재 조사 디자인 및 제작, 바이오 신약 manufacturing과 delivery까지 나노 바이오 전 분야에 대한 체계적인 연구를 수행하고 있다. 연구팀에서 가장 중점적으로 다루고 있는 핵심과제는 6개 분야로, ⑴나 노검출 및 이미징 ⑵질병 메커니즘 규명 및 타깃 선정 ⑶구조분석기반 신약 디자인 ⑷신약 후보 물질 제조 ⑸인 비보(In-vivo) 이미징 및 모델 테스팅 ⑹나노 전달 시스템으로 구분된다.

지금까지 신중훈 교수팀이 WCU사업의 지원을 받아 창출한 연구성과는 무수히 많다. 그 중 대표적인 연구결과를 꼽으면, 해 외학자 이상복 교수의 네이처 나노테크놀로지(Nature nanotechnology) 게재 논문, 국가과학자인 유룡 교수의 네이처(Nature) 논문, 창의적 연구사업단장인 이효철 교수의네이처

 

메소즈(Nature Methods)논 문, 박태관 교수의 네이처 머티리얼즈(Nature Materials) 논문 및 해외학자 윤석현 박사의 네이처 메소즈 논문 등이 있다. 이에 대해 신중훈 교수는 "2년간 네이처급 논문 5편을 발표했다는 것은 세계 어느 학과와 비교해도 자신 있는 연구 결과이다"라고 자신감을 표명하였다.

 

카이스트 신중훈 교수팀은 세 계 어느 학과에도 뒤지지 않는 연구성과를 도출하기 위해 해외학자와의 공동연구를 활발히 진행 하고 있다. 신중훈 교수팀과 함께 연구하고 있는 해외학자들은 우리나라에서 일할 수 있는 젊은 과학자들로 구성되어 있으며 , 대부분이 정식 카이스트 교수로 재직하고 있다. 또한 해외학자들이 소속되어 있는 해외 유명 대학과의 연구교류를 통해, 학생들이 직접 해당 대학에 가서 연구하는 등 학생들의 연구역량을 높일 수 있는 프로그램도 진행될 예정이다.

이렇듯 해외학자들과의 공동연구 및 해외 유수대학과의 교류는 WCU 육성사업을 지원 받았기에 가능할 수 있었다. 신중훈 교수는 "Idea without funding is just a dream(연구지원이 없는 아이디어는 단지 몽상일 뿐이다)"이라고 말하며, "이러한 학과가 있었으면 좋겠다는 꿈을 현실화할 수 있는 가능성을 찾았다"고 언급하였다.

또한 "해외에서 활약하고 있던 우수한 젊은 과학자들을 유치할 수 있었고, 이들을 통해 이전에는 상상할 수 없고 성사시키기 어려웠던 국제적 협력 관계를 쉽게 구축할 수 있었다"고 첨언하였다.

 

  

  

해외학자들과의 공동연구를 통 해 글로벌 인재를 양성하고 세계적 수준의 연구성과를 내겠다는 신중훈 교수팀의 장·단 기 연구 목표는 과연 무엇일까? 신중훈 교수는 "먼저 WCU 사업단이 국내·외 교육과 연구 체계에서 가시성 (visibility)과 인정(recognition)을 획득할 수 있는 존재감을 확보해야 할 것이고, 이후에는 이를 바탕으로 우수한 교수진과 학생들을 유치하여 세 계적인 연구진으로 발전해야 한다"라고 답변하였다. 향후 연구가 지금처럼 성실히 진행된다면, 도약에 필요한 지식과 인력 등이 제공되고, 국제적인 위상 확보와 홍보에도 가속도가 붙으리라는 기대감을 가지고 있다.

 

 

  

그러나 이 목표를 달성하기 위 해서는 앞으로 보완해야 할 사항도 있다. 이에 대해 신 교수는 "각 학교의 자율성을 인정 하는 유연한 감독체계가 필요하다"고 말한다. "계약에서 제시한 약속은 반드시 지켜야 하지만, 대학의 특수성 에 따른 다양성과 상황의 변화에 대해 인정해 주는 것도 필요하다. 해외학자라 하더라도 유럽, 아시아 및 미국의 상황이 다르고, 같은 미국이라 하더라 도 사립대, 연구소, 주립대 등 소속 여건에 따라 조건이 다르며, 같은 주립대라 하더라도 주에 따라 해외학자의 체류와 교육·연구 조건이 천차만별이므로, 이를 단순히 우리나라 국립대 조건으로 바꾸는 것은 보완되어야 한다고 생각한다"라고 설명하였다.

  

  

 

 

일반 현미경은 쥐의 혈관을 관 찰할 때 피부를 열어서 확인해야 하는 단점이 있었다. 그러나 공초점 현미경은 피부를 열어 보 지 않고도 피부 속의 혈관을 확인할 수 있다. 이 공초점 현미경은 의학에서 많이 활용되는데, 화면을 찍는 속도가 느 려 혈구가 지나가는 장면을 자세히 볼 수 없다는 단점이 있다. 그러나 윤석현 교수 실험실에서 쓰고 있는 공초점 현미경은 한 단계 업그레이드된 것으로, 모터 표면의 여러 각진 거울이 빠르게 돌면서 실시간으로 이미지를 볼 수 있다. 윤석현 교수 실험실의 공초점 현미경은 쥐를 헤치지 않고 마취한 상태에서 쥐의 혈관을 직접 이미징하여 실시간으로 볼 수 있는 장점이 있다. 이는 약물을 넣었을 때 어떤 전달 과정을 거치고, 혈관에 어떤 변화가 발생하며, 암세포가 어떻게 이동하는지를 명확히 알 수 있게 한다. 기존의 연구에서는 1분에 1장씩 사진을 찍어 데이터를 도출했다면, 윤 교수 실험실은 수 초 단위의 실시간 동영상으로 데이터를 만들 수 있다

  

관련링크 : http://webzine.nrf.go.kr/nrf_1005/html/re1.html

한국연구재단 웹진 2010년도 5월호 / 연구동향 - 연구현장탐방

[글로벌인재 양성을 위한 세계수준의 연구중심대학으로 도약 -카이스트 신중훈교수 연구팀]

  


참조 1 : http://webzine.nrf.go.kr/nrf_1005/html/re1.html




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OptokyCot

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